Tryptase CNV Test - Clinical
Elevated serum tryptase levels have been associated with a wide range of multi symptom complaints including:
- Cutaneous flushing, itching and severe allergic reactions
- Functional gastrointestinal symptoms
- Chronic pain
- Connective tissue abnormalities
A recent NIH study1 found that inherited increases in serum tryptase levels correlated with duplications (and triplications) of the gene encoding α-tryptase (TPSAB1).
Based on the results of this study, Gene By Gene has developed a clinical assay to identify people with multiple copies of α-tryptase. The test is now available for the out-of-pocket cost of $169*. For more information or to order the test, please contact Gene By Gene at firstname.lastname@example.org or (832)-761-9643.
*This test is not offered direct to consumer (DTC). It must be authorized by a qualified medical professional.
*This test is not currently available for New York State residents.
Lyons et al. Elevated basal serum tryptase identifies a multisystem disorder associated with increased TPSAB1 copy number. Nature Genetics volume 48, pages 1564–1569 (2016). https://www.nature.com/articles/ng.3696